Synthesis, Characterization and DNA Binding Studies of (E)-1-((Pyridin-2-yl)methylidene) semicarbazide Mn(II), Co(II), Ni(II) and Cu(II) Complexes

Main Article Content

Oinam U-wang
R. K. Bhubon Singh
W. Bembee Devi
U. Ibotomba Singh
R. K. Bindiya Devi
O. Bijeta Devi
Ramina .
Th. Surchandra Singh
Toka Swu

Abstract

(E)-1-((pyridin-2-yl)methylidene)semicarbazide (PMSC) complexes of [Mn(PMSC)2 ]Cl2 (1), [Co(PMSC)2]Cl2 (2), [Ni(PMSC)2]Cl2.5H2O (3), and [Cu(PMSC)(H2O)]Cl2 (4) have been synthesized and characterized by different spectroscopic techniques, EPR, magnetic susceptibility and thermal stability measurements. Complex 3 crystallizes as octahedral coordination complex in monoclinic crystal system. Complexes 1 and 2 have been found to have octahedral geometries and 4 to have square planar geometry. The complexes were found to be groove binding to calf-thymus DNA.

Keywords:
Schiff base, complex, DNA, groove binding.

Article Details

How to Cite
U-wang, O., Singh, R. K., Devi, W., Singh, U. I., Devi, R. K., Devi, O. B., ., R., Singh, T., & Swu, T. (2019). Synthesis, Characterization and DNA Binding Studies of (E)-1-((Pyridin-2-yl)methylidene) semicarbazide Mn(II), Co(II), Ni(II) and Cu(II) Complexes. Chemical Science International Journal, 26(2), 1-19. https://doi.org/10.9734/CSJI/2019/v26i230091
Section
Original Research Article