Chemical Composition of Anthocleista vogelii and Anti-oxidant Effect of Its Methanolic and Acetone Extracts

Main Article Content

E. E. Ikpe
U. D. Archibong
C. U. Michael
E. G. Ukpong

Abstract

This study entailed determination of chemical composition of Anthocleista vogelii and anti-oxidant effect of its methanolic and acetone extract. The phytochemical screening of Anthocleista vogelii showed quantitatively the presence of alkaloids, Tannins, Flavonoids, Saponins, Glycoside and phenols. The results from the proximate analysis indicated that the plant contained some important nutrient such as carbohydrate with percentage content of 16.07 – 34.67%, lipid 5.40 – 7.35%, and crude protein 2.23 – 2.41%. The mineral element analysis showed that potassium (K) was 32.6 – 41.1 mg/kg, sodium (Na) 5.41- 6.21 mg/kg, calcium 9.74 – 17.81 mg/kg, magnesium (mg) 5.71 – 32.0 mg/kg and Zn 0.32 – 0.68 mg/kg. The acetone and methanol leaves, stem bark and roots extracts of Anthocleista Vogelii exhibited reasonable scavenging activity in the DPPH (1, 1- diphenyl – 2- picrlhydrazyl) assay. The methnaolic extracts had a better inhibiting ability than acetone extract which could be attributed to higher content of tannin and Saponin in methanolic than acetone extract. The results were discussed with referenced to World Health Organization (WHO) standard of nutritional and medicinal values.

Keywords:
Analyses, Anthocleista vogelii, chemical composition, methanolic extracts

Article Details

How to Cite
Ikpe, E. E., Archibong, U. D., Michael, C. U., & Ukpong, E. G. (2020). Chemical Composition of Anthocleista vogelii and Anti-oxidant Effect of Its Methanolic and Acetone Extracts. Chemical Science International Journal, 29(8), 7-18. https://doi.org/10.9734/CSJI/2020/v29i830196
Section
Original Research Article

References

Shera SB, Rosemary IU. Nutritional and phytochemical compositions of leaves of Momordica balsamina (LINN) used in Herbal medicine in Northern Nigeria. Proceeding of the 37th Annual International Conference, Workshop and exhibition of chemical society of Nigeria (CSN). 2014;II:177 – 181.

Tiwari P, Kaur M, Kumar B, Kaur H. Phytochemical screening and Extraction A Review international pharmaceutical science. 2020;1:98-106.

Patel VP, Chu CT. Nuclear Transport, oxidative stress and Neurodegeneration. Int. J. Clin Exp. Pathol. 2011;4 (3):215-290.

Ebrahhimzadeh MA, Nabari SM, Nabavi SF, Bahramian F, bekhradinia AR. Antioxidant and free radical scavenging activity of H. Officially L. var. Augstitolius V. Odorata B. Hyrana and C. Speciosum, Pak, J. Pharm Sci. 2010;23(1):29-34.

Ikpe EE, Akpabio UD. Phytochemical screening and anti-tissue studies of aqueous and alcoholic extracts of Aneilema aequinoctiale. Elixir International Journal. 2013;58(2013):14868 –14873.

Onwuka GI. Food analysis and instrumentation theory of some Heavy metals in mangrove swamp flora in Niger Delta area of Nigeria. Tropical Journal of Environmental science and Health. 2011;4(i):11-14.

Harbone JB. Photochemistry. Academic press, London. 1993;21:2786.

Habila JD, Bello IA, Dzikwe AA, Musa H, Abubakar N. Total phenolic and antioxidant activity of Tridax procumbens linn. African journal of pharmacy and pharmacology. 2010;4(3):123–126.

Jimoh OF, Adedapo AA, Afolayan JA. Comparison of the Nutritive value, antioxidant and antibacterial activities of sonchus asper and Sochus Oleraceus. Rec. Nat. Prod. 2011;5(1):29–42.

Michael KI, David MP. The useful plant of West tropical African. Nig. J. Biochum, Mol. Biol. 2002;12:53-60.

Ikpe EE. Bioaccumulation of Heavy metals and hydrocarbons in mangrove swamp flora, fauna and sediment, Qua-Iboe River, Akwa Ibom State, Nigeria. A ph.D. Thesis, Chemistry Department, University of Benin, Benin City, Edo State, Nigeria. 2019;86-87.

Gwarzo US, Gimba CE, Adeyemo DJ, Paul ED. Nutritional, antinutritional and vitamins protire of ceratotheca sesamoids Endl. proceedings of the 37th Annual Int. conference workshop and exhibition of CSN. 2014;II.

Uchegbu RI, Okwu DE. An Evaluation the phytochemical and Nutrient composition of seeds and stem bark of Deuterium Senegalese Gmelina. Journal of Natural Science Research. 2012;5(2):107-111.

Pamela CC. Richard AH, Denis RF. LippinCOHS illustrated Reviews. Biochemistry 3rd. LippinCOH William and Wikins, Philadelphia. 2005;335–388.

Trease GE, Evans WC. Textbook on pharmacognosy. Balliere Tindal, London. 2001;56-66.

Liu RH. Potential synergy of phytochemicals in cancer prevention, mechanism of action. Journal of nutrition. 2004;134(12) 3279-3485.

Bruce PY. Organic chemistry 5th Pearson Education International USA. 2007;1319.

Okwu DE, Omodamiro OD. Effect of Hexane Extract and Phytochemical content of Xylopia eatkiopica and Ocimum gratissum on uterus of guenea pig. Bio-research. 2005;3:40-44.

Sodipo OA, Akiniyi JA, Ogunbarmera JV. Studies on certain characteristics of extract from bark of paningystalia macroceras. Global journal of pure and Applied sciences. 2000;6:83-87.

Salem K. How to Discover Abundant Health and Happiness. Morris Cerullo mission to all the world. San Diego, California. 2000;14.

Olajire AA, Azeez L. Total antioxidant activity, phenolic, flavonoid and Ascorbic acid content of Nigerian vegetable. African journal of food science and technology. 2011;2(2):022–029.

Michael WK. Medical Biochemistry. 3rd ed., Queen Mary publishers London. 2019;13-17.

Whelton PK, He J, Cutter JA, Brancati FL, Appel LJ, Follman D, Klag MJ. Effect of oral potassium on blood pressure. Meta-analysis of randomized controlled clinical trials. JAMA. 1997;277(20):16- 32.

World Health Organization. Lead poisoning and Health; 2018. Retrieved 17th February, 2019.

Pohl H, Wheeler R, John S, Murray HE. Sodium and potassium in Health and Disease. Spinger. 2013;13:29-47.

Odigie EK. Comparative Analysis of the phytochemical content, proximate composition, Heavy metal content and antioxidant activity of leaves, stem and root of Anthocleista Vogelii. An M.Sc dissertation, Chemistry Department, University of Benin, Benin City, Edo State, Nigeria; 2020.

Romani A. Magnesium in Health and Disease Springer. 2013;13:49–79.

Maret W. Zinc and Human disease. In Astrid sigel. Springer. 2013;13:389 -414.

Cherasse Y, Urade Y. Dietary Zinc Act as a sleep modulator. International Journal of Molecular Sciences. 2017;18(11):2334.

Prakash A, Bharti K, Majeed AB. Zinc Indications in brain disorders’’ fundam clin pharmacol. 2017; 29(2):131-149.

Wapnir RA. Protein Nutrition and Mineral Absorption. Boca Raton, florida CRC press; 1990.

Berdanier C, Dwyer D, Johnna T, Feldman E. Handbook of Nutrition and food. Boca Raton, florida: CEC press; 2017.