Functionalization of C=C Double Bonds of Pyrimidino-pyranoside Platform Groups

Issa Samb *

Organic and Therapeutic Chemistry Research Team (ECOT), University Alioune Diop, de Bambey, BP 30, Bambey, Sénégal.

Mohamed Lamine Gaye

Department of Chemistry, University Cheikh Anta DIOP, Dakar, Sénégal.

*Author to whom correspondence should be addressed.


In the search for peptidomimetic structures capable of mimicking endogenous peptides, we have studied the reactivity of C=C double bonds of pyrimidino-pyranoside platform groups. The exploitation of this reactivity by ozonolysis and reductive amination reactions allowed us to develop a fast and efficient route for the introduction of amine function capable of mimicking bioactive peptides.

Keywords: Pyrimidino-pyranoside, peptidomimetics, ozonolysis, reductive amination

How to Cite

Samb, I., & Gaye, M. L. (2023). Functionalization of C=C Double Bonds of Pyrimidino-pyranoside Platform Groups. Chemical Science International Journal, 32(5), 47–50.


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