Chemical Science International Journal 2021-07-31T10:27:45+00:00 Chemical Science International Journal Open Journal Systems <p style="text-align: justify;"><strong>Chemical Science International Journal&nbsp;(ISSN:&nbsp;2456-706X)&nbsp;</strong>aims to publish&nbsp;high quality papers (<a href="/index.php/CSIJ/general-guideline-for-authors">Click here for Types of paper</a>)&nbsp;in all aspects of chemical science. The journal also encourages the submission of useful reports of negative results. This is a quality controlled,&nbsp;OPEN&nbsp;peer reviewed, open access INTERNATIONAL journal.</p> Characterization and Antioxidant Activity of Myrianthus arboreus Seed Oil Harvested from Cote d’Ivoire 2021-07-13T11:45:23+00:00 Katou Yapo Séverin Koffi N’dri Emmanuel Gué Lieuné Alexis N’da Philippe Kessé Mamyrbekova-Békro Janat Akhanovna Békro Yves-Alain <p><strong>Aims: </strong>The rich and diversified Ivorian flora abounds in countless oilseed plants that certain rural populations use for the preparation of dishes. Thus, certain physical and chemical parameters and the fatty acid composition of the fat extracted from the seeds of <em>Myrianthus arboreus</em> from four towns in Côte d'Ivoire (Agboville; Bouaflé; Daloa and Man), were determined, in order to contribute to the development of this wild plant.</p> <p><strong>Methodology and Results:</strong> Physical and chemical parameters determined by dosage comply with Codex <em>Alimentarius</em> standards. These parameters vary according to the harvest area and they show that the oil of <em>Myrianthus arboreus</em> is rich in unsaturated compounds (Iv ˃ 90; Ri = 1.472 ± 0.001) The evaluation of the antioxidant activity, carried out by spectrophotometry by trapping the radical stable DPPH, showed a weak reduction of the stable radical DPPH by the oil of <em>Myrianthus arboreus</em> compared to vitamin C. This investigation also made it possible to determine for the first time the fatty acid composition of the oil of <em>Myrianthus arboreus</em> by GC / MS; more than 90% linoleic acid is the major acid.</p> <p><strong>Conclusion and Application:</strong> The oils analyzed showed very good contents of determined elements. Thus, the oil of <em>Myrianthus arboreus</em> could be used as well in human nutrition as in therapy. Thus, by its intrinsic characteristics, the oil from the seeds of <em>Myrianthus arboreus</em> is comparable to a conventional vegetable oil.</p> 2021-07-09T00:00:00+00:00 ##submission.copyrightStatement## Chemical Characterization and in Vitro Antioxidant Activity of Honey from Different Localities of Côte D’ivoire 2021-07-17T05:55:41+00:00 Kabran Guy Roger Mida Yeboue Koffi Apollinaire Adopo Sopie Sheilla Flavie Mamyrbékova-Békro Janat Akhanovna Békro Yves-Alain <p><strong>Aims: </strong>Although the honey produced in Côte d'Ivoire is widely used in households, there is no technical sheet mentioning its chemical composition. Thus, the present study aimed to fill this gap while studying the chemical composition and antioxidant power of eleven honey samples from nine localities in Côte d'Ivoire.</p> <p><strong>Methodology: </strong>The identification of secondary metabolites in the different honey samples was carried out by TLC and by color reaction tests. The quantification of these was performed by spectrophotometry. The antioxidant power of the honey samples was studied by DPPH and FRAP methods.</p> <p><strong>Results: </strong>All honey samples contains secondary metabolites from various families, with varying contents of total phenolic compounds and flavonoids. Overall, the honey samples showed a notable antioxidant profile, making them good free radical scavengers. The relationship established between the different variables analyzed showed in some cases positive and significant correlations.</p> <p><strong>Conclusion: </strong>The results of this study show that the honey produced in Côte d'Ivoire is of good quality. Therefore, its recurrent consumption could contribute to fighting certain pathologies caused by oxidative stress.</p> 2021-07-14T00:00:00+00:00 ##submission.copyrightStatement## Impact of Magnetic Field on the Dynamic Performance of Photovoltaic-Thermal Panel with Nanofluids 2021-07-19T11:54:45+00:00 S. Sami <p>The performance of a hybrid solar collector photovoltaic-thermal solar panel system under a magnetic field using nanofluids was presented hereby. A two-dimensional dynamic heat transfer and fluid flow model was developed to describe the behavior of the photovoltaic cell-thermal panel at different conditions such as solar irradiance, nanoparticles, different magnetic field gauss forces. different material properties, and boundary conditions. The model has been established after the dynamic mass and energy equations coupled with the heat transfer relationships, and thermodynamic properties as well as material properties under different magnetic gauss forces. Comparisons were made against literature data for validation purposes of the predictive model. The model fairly predicted the key parameters under different nanofluids conditions, magnetic fields, and compared well with existing data on the subject.</p> 2021-07-15T00:00:00+00:00 ##submission.copyrightStatement## Synthesis, Characterization and Antimicrobial Activities of Co (III) and Fe (III) Complexes of Imino-N-heterocyclic Carbenes Ligands 2021-07-31T10:27:45+00:00 Samaila Abubakar Musa Muktari Rejoice Atiko <p>The synthesis and antimicrobial application of Co (III) and Fe (III) complexes of imine functionalized <em>N</em>-heterocyclic carbene (Imino-NHC) ligands is reported. The ligand precursors 1-(2-[(hydroxyl-benzylidene)-amino]-ethyl)-3-R-3H-imidazol-1-ium bromide where R = pyridyl (1a) and benzyl (1b) have been reported in our previous work. The in-situ generated ligands of 1a and 1b have been successfully coordinated to CoBr<sub>2</sub> and [FeI(Cp)(CO)<sub>2</sub>] leading to the isolation of air-stable N^C^N^O four coordinate Co(III)&nbsp; complex 2 and a six-coordinate Fe(III) complex 3. The synthesised complexes were both found to be NMR inactive hence were characterize using FTIR and LRMS. The complexes were screened for antimicrobial activities against four gram-negative bacteria <em>Escherichia Coli (E-coli), Shigella, Klebsiella pneumoniae (K. Pneumoniae) </em>and <em>Salmonella typhi (S. typhi)</em> and a gram positive bacteria <em>Staphylocossus aureus (S. aureus).</em> The antimicrobial test was conducted using disc diffusion methods and based on the concentrations of 100, 200, 300, 400 and 500 µg/ mL, significant activities were recorded for both cobalt and the iron complexes.</p> 2021-07-31T00:00:00+00:00 ##submission.copyrightStatement## New Biological Targets in Fungi and Novel Molecule under Development: A Review 2021-07-19T05:56:58+00:00 Songuigama Coulibaly Jean-Paul D. U. N'guessan Alain Kacou Jean-Fabrice K. Koffi Amelanh S. Diakité Tanguy K. A. Kouaho Mahama Ouattara <p>Antifungal therapeutics is confronted today with the challenge of drug resistance of most fungal germs to current antifungal drugs. Faced with this situation, the search for new and more efficient antifungal molecules that avoid the phenomenon of drug resistance becomes an urgent task. The design of new antifungal drugs acting on new biological targets and/or by innovative mechanisms of action is essential in the fight against fungal infections. Current advances in molecular biology have identified new targets for the development of new antifungal therapy. Several biological targets for the development of new antifungal agents are currently being explored. Amongst these, the most promising are BET (Bromodomain and Extra-Terminal) proteins, Homoserine transacetylase (HTA), mannan cell wall, Glycosylphosphatidylinositols (GPI) anchor biosynthesis, Histone deacetylases, Sphingolipid biosynthesis, D9 fatty acid desaturase and Chitin biosynthesis. This review summarizes the new biological targets and their inhibitors under development as potential new antifungal drugs.</p> 2021-07-13T00:00:00+00:00 ##submission.copyrightStatement##