Chemical Science International Journal

We focused on a series of coumarin derivatives in this work. The method of Density Functional Theory (DFT) of quantum chemistry has been used at B3LYP / 6-31G (d, p) level in order to identify molecular descriptors which are useful for this study. The analysis of the statistical indicators allowed to obtain a QSAR model based on quantum descriptors and anti-cancer activity against breast cancer (MCF-7) that were accredited for good statistical performance. For the model, the statistical indicators were: correlation coefficient R² = 0.904, standard deviation S = 0.102, Fischer test coefficient F = 18.779 and correlation coefficient of cross validation

Microbial population and their activities in soil are important measure of soil biological activities as well as its health. The present study was conducted to access the impact of application of green manure and cellulose degrading bacterial consortium on the soil amylolytic bacterial population and amylase activity in rhizosphere of maize crop in field conditions. Soil amylolytic bacteria and amylase activity exhibited significant changes in response to application of consortium biofertilizer. The highest population of amylolytic bacteria was recorded during vegetative stage of maize crop in treatment T8 with 100%N + green manure+ consortium biofertilizer. Amylolytic population was found to be significantly higher in treatments having inorganic N + consortium biofertilizers as compared to control treatment. Soil amylase activity was significantly influenced by organic manure and vegetative growth stage. Highest amylase activity was recorded in treatment T8, whereas minimum activity was recorded in control (inorganic) treatment. Application of consortium biofertilizers significantly increased the amylase activity over treatments having solitary application of inorganic fertilizers. The results suggested that application of consortium biofertilizers on green manure boosted the colonisation and activities of amylolytic bacteria which directly influenced the available carbon pool as well as soil health.

We prepared 1-tosyl-2-trifluoroacetylindole - a novel example of an electron-deficient indole with an electrophilic C(3) position. This substance was involved in cyclocondensation with a variety of amidines to propose a new general pathway to 8H-[4,5-b]indolopyrimidines with yield 50-80%. CF₃-containing 5H-[3,2-d]indolopyrimidines were unknown before this study.

Twenty five different brands of sachet water produced in Ado-Ekiti metropolis have been analysed for drinking water quality using standard analytical method. The result obtained for all the water  samples indicated a pH range of 6.06 - 7.96, total solid (TS) 40.00 – 120.00 mg/l, total dissolved solids (TDS)  20.00 – 100.00 mg/l, turbidity ( 0.25 – 2.20 NTU) , conductivity ( 30.00 – 252.00 µ ohm/s), acidity 9 0.10 – 0.30 mg/l), chloride ( 28.40 – 50.11 mg/l) and nitrate (18.70 – 43.00 mg/l). Iron has the highest value (0.05 – 3.95 mg/l) in heavy metal analysis while concentrations of Pb, Cr and Ni were below detection limit in all samples. The total bacteria count (TBC) ranged between 1 and 8. The total coliform count (TCC) in almost all water samples was below detection limit. The physicochemical parameters of the analysed sachet water samples were within the WHO, NAFDAC and SON standards for drinking water. However it was observed that all the samples required chlorination prior to packaging.           

Management and disposing of used lubricating oil (ULO) poses deleterious effects to air, land and water pollution. These contaminants not only causes environmental problems, they also have bio-accumulation effects on living organisms, reduces the inhabitants lifespan as a result of the diseases spread, poisoning and fouling of catalyst as well as corrode processing equipment. The contaminants removal in used lubricating oil is a major step to avoid pollution as discussed thoroughly by many researchers in literature. In addition, to curbing pollution, another advantage is converting waste to wealth. This review paper presents insight into various methods for removal of contaminants in used lubricating oil. The advantages and drawbacks of each method were earmarked for further study.